rs13107325 is a single nucleotide polymorphism (SNP) in the SLC39A8 gene, which encodes the ZIP8 family metal‑ion transporter. The variant is a missense change that has been identified in population genetic studies and is commonly reported in clinical and research genetic panels. ZIP8 transports divalent metal ions including manganese and zinc across cell membranes. These metals serve as cofactors for multiple enzymes (for example, manganese‑dependent enzymes) and are important for processes such as glycosylation, antioxidant reactions, and metabolic enzyme function. Variation at rs13107325 is therefore biologically relevant because it can modify transporter behavior and downstream nutrient‑dependent pathways.

Because rs13107325 is a genetic variant rather than a serum analyte, interpretations focus on associated effects on transporter function. Genotypes linked to reduced ZIP8 activity are associated with altered cellular uptake of manganese and zinc, which can influence activity of manganese‑dependent enzymes and glycosylation patterns. Conversely, genotypes without that functional association generally reflect typical transporter activity and expected cellular metal handling. Any interpretation of variant effects is most informative when combined with the Nutrient Zoomer’s blood measures of vitamins, minerals, amino acids, and metabolic markers. Genetic associations point to tendencies in metal transport and nutrient processing but do not replace direct nutrient status testing or clinical context.

Nutrient Zoomer includes rs13107325 to add a genetics‑based lens on mineral transport and nutrient utilization. The marker evaluates inherited tendencies in zinc and manganese handling that can help explain unexpected nutrient panel results or persistent functional patterns, supporting more precise, individualized nutrition planning.