Escherichia coli Nissle, a strain of the Escherichia coli bacterium, is a notable probiotic first isolated in 1917 by German physician Alfred Nissle. Identified in the feces of a soldier who exhibited a remarkable resistance to gastrointestinal infections during World War I, this strain has since garnered attention for its beneficial effects on gut health. Unlike pathogenic strains of E. coli, E. coli Nissle 1917 is recognized for its ability to restore and maintain gut microbiota balance, alleviate symptoms of gastrointestinal disorders, and enhance immune response. Its use in clinical settings has been supported by numerous studies, leading to the development of probiotics and therapeutic applications aimed at managing conditions such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). As research continues, E. coli Nissle remains a key focus in the exploration of gut health and microbiome-based therapies.

Elevated levels of Escherichia coli Nissle may indicate a beneficial presence of this probiotic strain, which is associated with promoting gut health, enhancing the immune response, and protecting against pathogenic bacteria. These higher levels can reflect a balanced gut microbiome that supports overall well-being. Conversely, low levels of E. coli Nissle might suggest an imbalance in the gut microbiota, which could lead to gastrointestinal disturbances or increased susceptibility to infections. It may indicate a need for improved dietary strategies or probiotic supplementation to restore gut health and maintain microbial diversity.

Escherichia coli Nissle is featured in the Gut Zoomer panel, which assesses a comprehensive range of gut microbes, including beneficial, neutral, and potentially harmful species. This specific strain is known for its probiotic properties and ability to promote gut health by enhancing intestinal barrier function and modulating the immune response. By including Escherichia coli Nissle in the Vibrant Wellness Test, practitioners can gain insights into the gut microbiome's composition and functionality, aiding in the development of targeted strategies for improving digestive health and overall wellness.