Necator americanus is a parasitic nematode belonging to the Ancylostomatidae family, commonly known as the New World hookworm. First identified as a distinct species in the early 20th century, it is primarily recognized for its role in human intestinal health and disease. As a significant agent of hookworm infection, Necator americanus is predominantly found in tropical and subtropical regions, affecting millions of people worldwide. The parasite has a complex life cycle, transitioning from larvae in soil to adult worms residing in the human intestine, where it can cause anemia and nutritional deficiencies. Given its widespread impact on health, research into Necator americanus has expanded over the years, leading to its exploration as a potential bio marker in various medical tests, where it has been studied for its implications on immune response and gut health.

Elevated levels of Necator americanus may indicate a parasitic infection and suggest the presence of a strong immune response, often characterized by eosinophilia. This can be linked to symptoms such as abdominal pain, diarrhea, or fatigue, highlighting the need for further evaluation and potential treatment. Conversely, low levels of Necator americanus may suggest an absence of this parasite, which might be advantageous in terms of preventing the complications associated with parasitic infections. However, excessively low or absent levels could also point to potential immune dysregulation or lack of microbial diversity, which can impact overall gut health and immune function.

Necator americanus is included in the Gut Zoomer panel, which assesses the presence of key gut-related biomarkers to provide insights into parasitic infections and their impact on gut health. By detecting this intestinal hookworm, the test helps practitioners evaluate possible cause-effect relationships between parasitic load and various gastrointestinal symptoms, enabling tailored treatment options for achieving optimal wellness and balance.