What is Diphenyl Phosphate (DPP)? And Why Does the Toxin Zoomer Test for It?

Organophosphate flame-retardant metabolite

Diphenyl Phosphate (DPP) is a breakdown product formed when certain organophosphate flame retardants and related industrial chemicals are metabolized. It is measured in urine as a marker of recent environmental contact with these compounds. Tracking DPP helps clinicians identify patterns of chemical exposure and place those findings alongside detox genetics and other toxicants for clearer interpretation.

View Toxin Zoomer

Diphenyl Phosphate (DPP)

Quality and Security

High-quality testing run in a CLIA-certified and CAP-accredited lab in Santa Clara, California.

fortified-health-HIPAA-compliance-pqgjtx4popoe2n0arp68hrz8h2as5rlhgng5b2srk8 1

About Diphenyl Phosphate (DPP)

${ activeTab.tab_content.text }

View ${ activeTab.tab_content.btn_label }

About Diphenyl Phosphate (DPP)

Overview and History

Diphenyl Phosphate (DPP) is a small phosphate ester classified as an organophosphate metabolite. It is formed when triaryl or diaryl phosphate compounds used as flame retardants, plasticizers, or lubricants are hydrolyzed in the environment or after human exposure. DPP is not an endogenous human molecule but a xenobiotic marker. It is routinely measured in urine using high-sensitivity methods such as LC‑MS/MS. Over the past two decades, DPP and related metabolites have been used in population biomonitoring to track changing patterns of consumer- and industry-derived chemical exposures.

Interpreting Highs and Lows

Higher urinary DPP levels generally point to greater recent exposure to organophosphate flame retardants or related aryl phosphate compounds from sources like treated furniture, electronics, building materials, dust, or certain consumer products. Elevated values can also reflect timing of exposure (recent contact) or individual differences in metabolism and excretion. Lower or non-detectable DPP levels suggest little recent exposure to compounds that produce DPP, faster elimination, or that the person’s exposures involve different chemicals not metabolized to DPP. Interpretation requires the full Toxin Zoomer context, including other chemical markers, urine creatinine, exposure history, and detoxification genetics.

Featured Test

DPP is included in the Toxin Zoomer as a specific urinary marker of organophosphate-related chemical exposure. It helps identify household, product, or occupational sources of aryl phosphate contact and, when paired with detox genetics and other toxicant measurements, refines assessment of exposure patterns, clearance tendencies, and individualized priority areas for clinical evaluation.

View Toxin Zoomer

Diphenyl Phosphate (DPP) FAQs

What is Diphenyl Phosphate (DPP) and why is it important?

DPP is a urinary metabolite that shows up after exposure to certain organophosphate flame retardants and related industrial chemicals. It doesn’t have a normal role in the body but serves as a measurable sign of recent chemical contact. Knowing DPP levels helps clinicians map exposure sources and compare chemical load alongside other markers and detox genetics.

What does it mean if my Diphenyl Phosphate (DPP) levels are low?

Low or undetectable DPP usually means little recent exposure to chemicals that break down into DPP, or that any exposure happened long enough before sampling for the body to excrete it. It can also reflect faster metabolism or that exposures involve different compounds not measured by DPP. Results are best understood with other panel findings and your exposure history.

What does it mean if my Diphenyl Phosphate (DPP) levels are high?

High urinary DPP suggests more recent or greater exposure to organophosphate flame retardants or related aryl phosphate compounds, or differences in how your body metabolizes and clears these chemicals. Elevated levels flag an exposure pattern but do not by themselves indicate health outcomes; interpretation should use the full Toxin Zoomer report and clinical context.

Why is Diphenyl Phosphate (DPP) measured on the Toxin Zoomer?

DPP provides a targeted measure of exposure to a class of flame retardants and related chemicals commonly found in household products and building materials. Including DPP helps clinicians link lab data to likely exposure sources and, when combined with detox genetics and other markers, improves individualized assessment of chemical burden and clearance capacity.

Browse Articles

How Mycotoxins Trigger Mast Cell Activation and Brain Inflammation

Many patients with chronic, unexplained symptoms have a history of mold exposure that’s never been fully explored. What begins as vague fatigue or hea...

Brendan Vermeire

Aug 13, 2025

Neural Health Toxins

How Toxin Exposure Impacts Your Cardiometabolic Health

A common theme among many of my nutrition clients is that despite eating well, staying active, and managing stress, they feel worn down, inflamed, and...

Leslie Weidner, RDN

Aug 13, 2025

Cardiovascular Health Toxins Longevity

Heavy Metals: Exposure, Oxidative Stress, & Disease Development

Heavy metals are found naturally on Earth in soil, rocks, bodies of water, and in trace amounts inthe atmosphere. However, human activities have alter...

Jamie Haleva

Jul 2, 2025

Toxins Longevity

The Impact of Endocrine Disruptors on Menopause: Exposure, Testing, and Solutions

By some estimates, environmental factors may be the cause of 24% of human diseases and disorders around the world, according to the Endocrine Society....

Leslie Weidner, RDN

Apr 23, 2025

Hormones Toxins

About Vibrant:

The Experts Behind  Every Test

Our team is built on collaboration across disciplines to advance the science of wellness and longevity. At Vibrant Wellness, lab scientists, technologists, clinical researchers, doctors, practitioners, longevity advisors, engineers, and regulatory experts work side by side to transform diagnostics.

By uniting diverse expertise under one mission, we pioneer precision testing that empowers providers to uncover root causes, personalize care plans, and optimize patient health outcomes. Every test we develop reflects this commitment—to push boundaries in functional medicine, deliver clear, actionable insights, and support clinicians in helping patients live healthier, longer lives.

View All Tests

Results trusted by over 18,000 functional wellness professionals

We’re the leading provider of specialty wellness lab testing because we develop our testing with rigorous, ongoing research by top clinical experts, doctors, and scientists.

The gold standard of accuracy in  the lab industry

Our tests run on a proprietary 3Dense microchip technology platform that boasts unrivaled specificity and sensitivity. While most other labs carry only CLIA certification, we're CAP-accredited by the College of American Pathologists.

Our Clinical Support Team

We understand that patient care doesn't end with diagnosis. To achieve Vibrant health, patients need clinical support and
obtainable lifestyle changes. Our clinical support team helps providers make informed treatment recommendations, resulting in  better patient outcomes.

Mary Beth Augustine

DCN, RDN, FAND- Lead Clinical Educator

Suzanne Barker

MS, RDN, LD, CTTS, CGP- Clinical Educator

Suzette Garcia

MSc- MHNE- Clinical Educator

Brooke Mader Ganev

MS, CNS, LDN, FDN- Clinical Educator

Adair Anderson

MS, RDN, LDN- Clinical Educator

Lillie Luu Nguyen

DCN, CNS, LDN- Clinical Educator

Jason Barker

ND- Clinical Educator

Emaline Brown

ND- Clinical Educator

Dana Filatova

DCN, CNS, LDN- Clinical Educator

Jessy Dhanjal

ND- Clinical Educator

Nour Amri

MS, LDN, CNS, CKNS- Clinical Educator

Ready to Elevate Your Approach to Precision Wellness?

At Vibrant Wellness, we’re redefining the future of diagnostics—making complex science clear, accessible, and actionable. Whether you're a provider advancing personalized care or a patient seeking data-driven answers, our precision testing gives you the clarity to make informed decisions. Experience the next generation of functional medicine through clinically validated insights and seamless testing solutions.

Become a Provider

Become a Patient