Cardio Genetics

The Cardio Genetics test is a cutting-edge analysis of your DNA, designed to uncover inherited risk factors that contribute to heart disease, stroke, and metabolic disorders. Using a simple blood sample, this test evaluates key genetic variants (SNPs) involved in cholesterol metabolism, blood pressure regulation, inflammation, blood clotting, and drug response. In partnership with your healthcare provider, Cardio Genetics provides a detailed report showing how your unique genetic profile impacts cardiovascular risk, often before symptoms appear or standard labs could be abnormal. The test empowers you and your provider with actionable, precision medicine insights to support personalized prevention, early intervention, and lifelong heart health.

You may benefit from this test if you have:

Family history of heart disease or stroke

High blood pressure

High cholesterol or triglycerides

Unexplained fatigue or shortness of breath

Personal or family history of blood clots, heart attack, or stroke

Diabetes or prediabetes

Struggles with weight

Elevated inflammation on labs

Concerns about inherited heart risk

Irregular heartbeat or arrhythmia

Poor circulation or cold hands/feet

Unusual reactions to heart medications

Cardio Genetics

Get Started

What We Measure

45 Lipid Metabolism & Transport Markers

4 Clotting & Thrombosis Markers

9 Inflammation & Oxidative Stress Markers

18 Pharmacogenomics Markers

44 Vascular Function & Blood Pressure Markers

45 Lipid Metabolism & Transport Markers

4 Clotting & Thrombosis Markers

9 Inflammation & Oxidative Stress Markers

18 Pharmacogenomics Markers

44 Vascular Function & Blood Pressure Markers

Sample Info

Blood

NY State Unavailable

Turnaround Time：10 Days

Resources

Sample Report

Collection Instructions

Learn More

You may benefit from this test if you have:

Family history of heart disease or stroke

High blood pressure

High cholesterol or triglycerides

Unexplained fatigue or shortness of breath

Personal or family history of blood clots, heart attack, or stroke

Diabetes or prediabetes

Struggles with weight

Elevated inflammation on labs

Concerns about inherited heart risk

Irregular heartbeat or arrhythmia

Poor circulation or cold hands/feet

Unusual reactions to heart medications

Precision Testing You Can Trust

All of our laboratory tests are performed in a CLIA-certified and CAP-accredited facility in California

Why Choose Cardio Genetics

Lipid Metabolism Genes

Clotting & Coagulation Pathways

Inflammation & Endothelial Function

Pharmacogenomics (Drug Response Genes)

Blood Pressure, Stress, & Hormonal Regulation

Integrated Genetic Risk Profiling

Lipid Metabolism Genes

Your genes play a key role in how your body makes, transports, and clears cholesterol and triglycerides, two of the most important factors in heart health. Variants in genes like APOE, APOA5, LPL, and PCSK9 influence how fats are processed in the bloodstream, affecting LDL (“bad” cholesterol), HDL (“good” cholesterol), and triglyceride levels. These genetic differences help explain why some people maintain healthy cholesterol through diet alone, while others need additional support. Understanding your lipid-related genes empowers you and your provider to create a truly personalized plan for diet, supplements, and medications that keep your heart and arteries healthy for life.

Clotting & Coagulation Pathways

Your DNA can reveal how your blood responds to injury, stress, or inflammation, key factors in preventing dangerous clotting events. Variants in genes such as Factor V Leiden (F5), Prothrombin (F2), and MTHFR affect clot formation and breakdown, while others like ACE and BDKRB2 influence vessel constriction and platelet function. Knowing these inherited tendencies can be life-saving, especially for individuals with a personal or family history of blood clots, stroke, or cardiovascular disease. This insight enables your provider to guide safer preventive care, especially when considering hormone therapy, surgery, or medications that affect blood viscosity.

Inflammation & Endothelial Function

Disrupted lipid metabolism is a silent driver of cardiovascular disease and is deeply influenced by genetics. Variants in APOA5 and LPL affect triglyceride clearance and remnant particles, while APOE isoforms shape lipoprotein transport and PCSK9/LDLR variants regulate LDL-receptor activity and LDL levels. When these pathways are unbalanced, triglycerides rise, atherogenic remnants and small dense LDL accumulate, and plaque formation accelerates, often before symptoms appear. Testing for these variants reveals a genetic tendency toward atherogenic lipids, enabling earlier intervention with targeted nutrition, lifestyle strategies, and personalized therapy to protect long-term vascular health.

Pharmacogenomics (Drug Response Genes)

Your genetics don’t just influence disease risk, they shape how you respond to cardiovascular therapies. Variants in ACE and AGTR1 affect RAAS-targeting drugs (ACE inhibitors/ARBs); CYP11B2 relates to aldosterone biology and may inform mineralocorticoid antagonist strategies; NOS3 (endothelial NO synthase) influences vasodilatory tone, relevant to nitrates and vascular reactivity. The HPA–RAAS connection ties stress hormones to vascular responses that impact treatment needs.

Blood Pressure, Stress, & Hormonal Regulation

Genes influence how your body maintains blood pressure, manages stress, and balances hormones, all key drivers of heart health. Variants in ACE, AGTR1, CYP11B2, and NOS3 help regulate sodium retention, vascular tone, and hormonal feedback systems like the renin–angiotensin pathway. When these genes are imbalanced, they can contribute to elevated blood pressure, fluid retention, and reduced stress resilience. Understanding these inherited tendencies allows for targeted approaches that include diet modification, stress management, and personalized medication support to protect your heart and circulatory system over time.

Integrated Genetic Risk Profiling

Cardio Genetics profiles key cardiovascular variants, highlighting LPA (which drives lifelong Lp(a) levels and oxidized-LDL cargo) and the 9p21 coronary risk locus, alongside genes affecting cholesterol handling, blood pressure, inflammation, clotting, and medication response. Because DNA doesn’t change, this one-time test provides lifelong insight into inherited risk and resilience, with each result linked to clear, evidence-based recommendations so you and your provider can target prevention, personalize therapy, and plan long-term follow-up.

Vibrant Advantage

Cardio Genetics offers a next-generation approach to cardiovascular risk, providing a deep analysis of your DNA to uncover inherited drivers of heart disease, all from a single, easy sample. This advanced genetic test delivers clinically validated, actionable insights, empowering you and your provider to make informed decisions and support long-term heart health.

Screens 100+ key genes related to cholesterol, blood pressure, clotting, inflammation, and drug metabolism, giving you a holistic understanding of your personal risk for heart disease and stroke.

Links your unique genetic variants to specific heart risks and medication responses, enabling highly personalized management and smarter preventive strategies.

Can help reveal genetic risks even when there could be no symptoms or known family patterns, helping you and your provider take proactive action earlier.

Your report connects gene findings directly to clinical recommendations, making it simple to see how your DNA affects heart health and what steps to take next.

Cardio Genetics is clinically validated to deliver reliable, actionable information for managing cardiovascular risk, empowering you to take control of your health for years to come.

Cardio Genetics Key Markers

Additional Resources

What's included

Complete Markers List

Patient One Pager

Key Clinical Messages

Sample Report

Complete Markers List

Patient One Pager

Key Clinical Messages

Sample Report

Step 1

Order

Ask your provider to order your lab test

Step 2

Collect

Use easy to follow instructions included in your test kit

Step 3

Return

Use the included return label to send back your samples

Step 4

Receive

Your provider will receive your results in 2-3 weeks

Cardio Genetics

Cardio Zoomer

Why It Matters

Cardio Genetics uncovers inherited risks for cholesterol, blood pressure, clotting, inflammation, and drug response, enabling personalized management and early intervention for heart disease and stroke. When paired with Cardio Zoomer, it connects your DNA to real-time cardiovascular changes for a complete risk assessment.

Cardio Zoomer analyzes advanced lipid markers, inflammation, oxidative stress, endothelial function, clotting, and metabolic markers to reveal hidden risk factors and support precision prevention. Paired with Cardio Genetics, it clarifies how your genes and current biomarkers interact to shape heart health.

Key Insights

Identifies gene variants driving high cholesterol, hypertension, abnormal clotting, medication response, and hidden inflammatory risk, even in the absence of symptoms or abnormal labs.

Detects early signs of vascular damage, chronic inflammation, abnormal lipids, and metabolic dysfunction. When combined with Cardio Genetics, it helps pinpoint who’s most at risk and why.

What’s Measured

Screens 100+ genes covering cholesterol/lipids, blood pressure, clotting, inflammation, and pharmacogenomics, translating your DNA into actionable insights for cardiovascular management.

Measures cholesterol subtypes, ceramides, advanced lipid and inflammatory markers, oxidative stress, endothelial function, clotting and cardiac stress markers, and metabolic indicators.

Cardio Genetics

Why It Matters

Key Insights

Identifies gene variants driving high cholesterol, hypertension, abnormal clotting, medication response, and hidden inflammatory risk, even in the absence of symptoms or abnormal labs.

What’s Measured

Screens 100+ genes covering cholesterol/lipids, blood pressure, clotting, inflammation, and pharmacogenomics, translating your DNA into actionable insights for cardiovascular management.

Cardio Zoomer

Why It Matters

Key Insights

Detects early signs of vascular damage, chronic inflammation, abnormal lipids, and metabolic dysfunction. When combined with Cardio Genetics, it helps pinpoint who’s most at risk and why.

What’s Measured

Measures cholesterol subtypes, ceramides, advanced lipid and inflammatory markers, oxidative stress, endothelial function, clotting and cardiac stress markers, and metabolic indicators.

What is the Cardio Genetics test and how does it work?

The Cardio Genetics test is a cutting-edge DNA analysis that identifies inherited risk factors for heart disease, stroke, high cholesterol, clotting problems, and medication response. Using a simple saliva or blood sample, it screens for 100+ key genes linked to cardiovascular health. Advanced laboratory technology provides you and your provider with a clear, actionable report, making it easier to personalize your management plan and take proactive steps to protect your heart.

Who should consider taking the Cardio Genetics test?

What makes Cardio Genetics different from other heart risk tests?

How does Cardio Genetics help identify the root cause of cardiovascular risk?

How do I order the Cardio Genetics test and what should I expect?

Regulatory Statement

Limitations

Please note the information provided by Vibrant Wellness is intended solely for research and informational purposes to help inform lifestyle choices aimed at potential risk mitigation. The information is not intended to be used by the patient for any diagnostic purpose and is not a substitute for medical advice by a healthcare practitioner. Please consult a licensed healthcare practitioner for any questions regarding diagnosis, prevention, or treatment of any disease or health assessment.

The test is not available in NY State.

Regulatory Disclaimer

Please note the information provided by Vibrant Wellness is intended solely for research and informational purposes to help inform lifestyle choices aimed at potential risk mitigation. The tests were developed, and their performance characteristics were determined by Vibrant America and Vibrant Genomics. They have not been cleared or approved by US Food and Drug Administration. The laboratory is certified under the Clinical Laboratory Improvements Amendments (CLIA) as qualified to perform high complexity testing. The laboratory is also in compliance with College of American Pathologists (CAP) regulations and New York State Department of Health (NYSDOH) regulations.

Cardio Genetics

You may benefit from this test if you have:

Cardio Genetics

What We Measure

Sample Info

NY State Unavailable

Resources

You may benefit from this test if you have:

Precision Testing You Can Trust

Why Choose Cardio Genetics

Lipid Metabolism Genes

Clotting & Coagulation Pathways

Inflammation & Endothelial Function

Pharmacogenomics (Drug Response Genes)

Blood Pressure, Stress, & Hormonal Regulation

Integrated Genetic Risk Profiling

Vibrant Advantage

Cardio Genetics Key Markers

Additional Resources

How it works

Order

Collect

Return

Receive

Synergistic Testing with Cardio Zoomer

FAQs for Cardio Genetics

What is the Cardio Genetics test and how does it work?

Who should consider taking the Cardio Genetics test?

What makes Cardio Genetics different from other heart risk tests?

How does Cardio Genetics help identify the root cause of cardiovascular risk?

How do I order the Cardio Genetics test and what should I expect?

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