Toxin Genetics

SNP Prevalence and Clinical References

This page provides prevalence data for the individual SNPs among different ethnicities along with clinical references that show the risk associations. 

rs1042157
Functional genetic variants in the 3'-untranslated region of sulfotransferase isoform 1A1 (SULT1A1) and their effect on enzymatic activity
rs762551
The genetic profiles of CYP1A1, CYP1A2 and CYP2E1 enzymes as susceptibility factor in xenobiotic toxicity in Turkish population
Induction of CYP1A2 by heavy coffee consumption is associated with the CYP1A2 -163C>A polymorphism
rs1871042
Antioxidant-Rich Diet, GSTP1 rs1871042 Polymorphism, and Gastric Cancer Risk in a Hospital-Based Case-Control Study
GSTP1 rs1695 and rs1871042, and SOD2 rs4880 as molecular markers of lipid peroxidation in blood storage
rs713041
Association of genetic variants in the GPX1 and GPX4 genes with the activities of glutathione-dependent enzymes, their interaction with smoking and the risk of acute pancreatitis
Single nucleotide polymorphism analysis of 3'UTR rs713041 of Glutathione peroxidase 4 association with susceptibility to oral premalignant disorders
Genetic Biomarkers of Metabolic Detoxification for Personalized Lifestyle Medicine
rs2234922
Association of the genetic polymorphism of EPHX1 and EPHX2 with the susceptibility to chronic benzene poisoning
rs1051741
Association of the genetic polymorphism of EPHX1 and EPHX2 with the susceptibility to chronic benzene poisoning
rs751141
Association of the genetic polymorphism of EPHX1 and EPHX2 with the susceptibility to chronic benzene poisoning
rs1902023
Exposure of Slovenian children and adolescents to bisphenols, parabens and triclosan: Urinary levels, exposure patterns, determinants of exposure and susceptibility
rs1048943
Sequence Polymorphism in Xenobiotic Metabolising Genes in Iraqi Colorectal Cancer Patients
rs1056836
Polymorphisms and diazinon and malathion levels in the etiology of breastcancer: a case-controlstudy in Mazandaran Province, North of Iran
CYP1B1 L432V Polymorphism and Lung Cancer Risk in the Iranian Population
Polymorphism of Glutathione S-transferase Genes and the Risk of Toxic Liver Damage in Petrochemical Workers
As3MT and GST Polymorphisms Influencing Arsenic Metabolism in Human Exposure to Drinking Groundwater
Genetic Variations of Glutathione S-Transferase Influence on Blood Cadmium Concentration
Chronic Mercury Exposure and GSTP1 Polymorphism in Munduruku Indigenous from Brazilian Amazon
Genetic Polymorphisms and Pesticide-Induced DNA Damage: A Review
rs1138272
A prospective validation pharmacogenomic study in the adjuvant setting of colorectal cancer patients treated with the 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX4) regimen
rs11076161
A polymorphism in metallothionein 1A (MT1A) is associated with cadmium-related excretion of urinary beta 2-microglobulin
Association of MT1A rs11640851, rs8052394 and rs11076161 Polymorphisms with the Risk of Developing Breast Cancer: A Haplotype-Based Case-Control Study and in Silico Analysis
rs1050450
Association between genetic variations in GSH-related and MT genes and low-dose methylmercury exposure in children and women of childbearing age: a pilot study
Interaction of Smoking and Lead Exposure among Carriers of Genetic Variants Associated with a Higher Level of Oxidative Stress Indicators
rs2056131
Mold allergen sensitization in adult asthma according to integrin β3 polymorphisms and Toll-like receptor 2/+596 genotype
rs28383151
Polymorphisms in the coding region of X-ray repair complementing group 4 and aflatoxin B1-related hepatocellular carcinoma
rs3734091
Genetic polymorphisms in DNA repair genes XRCC4 and XRCC5 and aflatoxin B1-related hepatocellular carcinoma
rs25487
Interaction of DNA repair gene polymorphisms and aflatoxin B1 in the risk of hepatocellular carcinoma
rs861539
Interaction of DNA repair gene polymorphisms and aflatoxin B1 in the risk of hepatocellular carcinoma
rs7003908
DNA repair gene XRCC7 polymorphisms (rs#7003908 and rs#10109984) and hepatocellular carcinoma related to AFB1 exposure among Guangxi population, China
rs13181
Interaction of DNA repair gene polymorphisms and aflatoxin B1 in the risk of hepatocellular carcinoma
rs2228001
Interaction of DNA repair gene polymorphisms and aflatoxin B1 in the risk of hepatocellular carcinoma
rs1048943
Sequence Polymorphism in Xenobiotic Metabolising Genes in Iraqi Colorectal Cancer Patients
rs1056836
Polymorphisms and diazinon and malathion levels in the etiology of breastcancer: a case-controlstudy in Mazandaran Province, North of Iran
CYP1B1 L432V Polymorphism and Lung Cancer Risk in the Iranian Population