What is Aquaporins (7) and Why Does the Food Zoomer Test for It?

Membrane water-channel proteins

Aquaporins are membrane channel proteins that control water and small solute movement across cell membranes. Measuring antibodies to Aquaporins (7) can reveal immune recognition of food-derived aquaporin proteins and help distinguish mucosal versus systemic response patterns. This information complements other IgA/IgG food reactivity data to clarify dietary immune signals.

View Food Zoomer

Aquaporins (7)

Quality and Security

High-quality testing run in a CLIA-certified and CAP-accredited lab in Santa Clara, California.

fortified-health-HIPAA-compliance-pqgjtx4popoe2n0arp68hrz8h2as5rlhgng5b2srk8 1

About Aquaporins (7)

${ activeTab.tab_content.text }

View ${ activeTab.tab_content.btn_label }

About Aquaporins (7)

Overview and History

Aquaporins belong to the major intrinsic protein (MIP) family of membrane water channels. First identified in the early 1990s and awarded the Nobel Prize to Peter Agre in 2003 for aquaporin discovery, these proteins are conserved across plants, animals, and microbes and typically form small (~25–35 kDa) pore-forming subunits. In plants, aquaporins regulate water flow, cell turgor, and transport of small neutral solutes; in animals they mediate rapid water movement in organs like kidney and gut. Structurally they share characteristic pore motifs and can be present in dietary plant tissues, where protein fragments may be recognized by the immune system measured in Food Zoomer.

Interpreting Highs and Lows

Elevated antibody levels to Aquaporins (7) may indicate prior or ongoing immune recognition of food-derived aquaporin proteins, reflecting exposure, sensitization, or cross-reactivity with similar proteins. Higher IgA suggests mucosal (gut) immune engagement, while higher IgG points to broader systemic antibody response. Low or absent antibodies may reflect limited exposure, oral tolerance, or lack of immune recognition. Any single aquaporin result is most informative when interpreted alongside the full Food Zoomer pattern and clinical context.

Featured Test

Aquaporins (7) are included to detect immune responses to plant-derived water-channel proteins that appear in many foods. Measuring antibodies to these proteins helps map whether immune activity clusters around lectins and related plant families, supporting more precise dietary pattern interpretation and personalized nutrition planning.

View Food Zoomer

Aquaporins (7) FAQs

What is Aquaporins (7) and why is it important?

Aquaporins (7) refers to a set of water-channel proteins that can be present in foods. When fragments of these proteins enter the gut, the immune system may produce IgA or IgG antibodies against them. Tracking those antibody levels helps show whether the body is recognizing these food-derived proteins and how that recognition fits with other food immune patterns.

What does it mean if my Aquaporins (7) levels are low?

Low antibody levels suggest limited immune recognition of aquaporin proteins—either due to low dietary exposure or oral tolerance. Low results can indicate the immune system is not mounting a measurable mucosal or systemic response to these proteins. Interpreting low results is most meaningful when compared with other Food Zoomer markers and clinical information.

What does it mean if my Aquaporins (7) levels are high?

Higher antibody levels indicate the immune system has recognized aquaporin-derived protein fragments and mounted a mucosal (IgA) or systemic (IgG) response. Elevated results may reflect repeated exposure, sensitization, or cross-reactivity with similar proteins; they do not by themselves indicate a specific condition. Clinical context and the rest of the Food Zoomer panel are needed to interpret patterns and relevance.

Why is this biomarker included in the Food Zoomer?

Including Aquaporins (7) lets providers detect immune activity to a class of plant proteins that can appear across many foods. This marker helps reveal clustering of reactivity around plant families and lectin-related proteins, improving pattern recognition and supporting targeted dietary decisions based on the full IgA/IgG profile.

Browse Articles

Gluten and Autoimmunity: What Celiac Clues Might Be Hiding

Gluten, a protein found in wheat, barley, rye, and related grains, is a staple in many diets worldwide. And for many individuals, it’s harmless to con...

Nancy Guberti, M.S., C.N.

Jul 2, 2025

Autoimmunity Food Reactions

Food Sensitivity vs. Allergies: What's the Difference?

Food Sensitivities vs. Allergies: Understanding the Difference with Advanced Testing

Many patients struggle with chronic symptoms like bloating, fatigue, and migraines but don’t get clear answers from standard allergy tests. As a healt...

Melissa Brescia

Mar 31, 2025

Food Reactions

Vibrant Research Spotlight: Food Sensitivity Clinical Trial

Food sensitivities can significantly impact health, causing symptoms like gastrointestinal distress, skin issues, and fatigue. Diagnosing and treating...

Jamie Haleva

Jul 29, 2024

Food Reactions Research & Innovation

The Link Between Diet and Disease: Insights from Food Sensitivity Testing

The diet and disease relationship is well established and has gained significant attention in the face of chronic ailments that may be rooted in poor ...

Jamie Haleva

Jul 15, 2024

Autoimmunity Food Reactions Longevity

About Vibrant:

The Experts Behind  Every Test

Our team is built on collaboration across disciplines to advance the science of wellness and longevity. At Vibrant Wellness, lab scientists, technologists, clinical researchers, doctors, practitioners, longevity advisors, engineers, and regulatory experts work side by side to transform diagnostics.

By uniting diverse expertise under one mission, we pioneer precision testing that empowers providers to uncover root causes, personalize care plans, and optimize patient health outcomes. Every test we develop reflects this commitment—to push boundaries in functional medicine, deliver clear, actionable insights, and support clinicians in helping patients live healthier, longer lives.

View All Tests

Results trusted by over 18,000 functional wellness professionals

We’re the leading provider of specialty wellness lab testing because we develop our testing with rigorous, ongoing research by top clinical experts, doctors, and scientists.

The gold standard of accuracy in  the lab industry

Our tests run on a proprietary 3Dense microchip technology platform that boasts unrivaled specificity and sensitivity. While most other labs carry only CLIA certification, we're CAP-accredited by the College of American Pathologists.

Our Clinical Support Team

We understand that patient care doesn't end with diagnosis. To achieve Vibrant health, patients need clinical support and
obtainable lifestyle changes. Our clinical support team helps providers make informed treatment recommendations, resulting in  better patient outcomes.

Mary Beth Augustine

DCN, RDN, FAND- Lead Clinical Educator

Suzanne Barker

MS, RDN, LD, CTTS, CGP- Clinical Educator

Suzette Garcia

MSc- MHNE- Clinical Educator

Brooke Mader Ganev

MS, CNS, LDN, FDN- Clinical Educator

Adair Anderson

MS, RDN, LDN- Clinical Educator

Lillie Luu Nguyen

DCN, CNS, LDN- Clinical Educator

Jason Barker

ND- Clinical Educator

Emaline Brown

ND- Clinical Educator

Dana Filatova

DCN, CNS, LDN- Clinical Educator

Jessy Dhanjal

ND- Clinical Educator

Nour Amri

MS, LDN, CNS, CKNS- Clinical Educator

Ready to Elevate Your Approach to Precision Wellness?

At Vibrant Wellness, we’re redefining the future of diagnostics—making complex science clear, accessible, and actionable. Whether you're a provider advancing personalized care or a patient seeking data-driven answers, our precision testing gives you the clarity to make informed decisions. Experience the next generation of functional medicine through clinically validated insights and seamless testing solutions.

Become a Provider

Become a Patient