What is Ara h 13 and Why Does the Food Zoomer Test for It?

Peanut seed protein marker

Ara h 13 is a peanut-derived seed protein that can be targeted by the immune system. Measuring IgA and IgG reactivity to Ara h 13 helps reveal whether immune recognition of peanut proteins is predominantly mucosal or systemic when viewed within the full Food Zoomer panel.

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Ara h 13

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About Ara h 13

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About Ara h 13

Overview and History

Ara h 13 is named from Arachis hypogaea (peanut) allergen nomenclature and represents a specific peanut seed protein detectable at the peptide level. It is part of the catalog of peanut-derived proteins studied for immune recognition and is included in research and clinical panels alongside other Ara h family members. Historically, Ara h proteins were identified through allergen profiling of peanut seed extracts; many serve structural or defense roles in the seed (for example, oil-body associated proteins, storage proteins, or small defense peptides). Biochemically, Ara h 13 behaves as a discrete peptide/protein antigen that can be bound by antibodies, making it useful for detailed peptide-level immune mapping.

Interpreting Highs and Lows

Elevated IgA or IgG reactivity to Ara h 13 indicates measurable immune recognition of that peanut protein—IgA elevations often point to mucosal (gut-associated) antibody activity, while IgG elevations reflect systemic antibody responses. Low or absent reactivity suggests limited immune contact with Ara h 13, tolerance, or that other peanut proteins are the dominant targets. Any interpretation should be made in the context of the full Food Zoomer profile (other peanut peptides, IgA vs IgG patterns) and clinical history, since single-marker results are one piece of a broader immune pattern.

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Ara h 13 is included to expand peptide-level coverage of peanut antigens, allowing the Food Zoomer to detect which specific peanut proteins the immune system recognizes. That specificity helps clarify whether peanut-related reactivity clusters with mucosal or systemic patterns and supports more precise, personalized dietary planning.

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Ara h 13 FAQs

What is Ara h 13 and why is it important?

Ara h 13 is one of several proteins produced in peanut seeds that can be recognized by the immune system. When antibodies bind Ara h 13, it shows up on antibody-based food panels like Food Zoomer. Knowing whether the immune system reacts to Ara h 13 helps clinicians see if peanut proteins are part of a wider food-related immune pattern.

What does it mean if my Ara h 13 levels are low?

Low or undetectable Ara h 13 antibodies generally mean there is little measurable immune response to that specific peanut protein, which can reflect limited exposure or tolerance. By contrast, higher levels suggest immune recognition from past or ongoing exposure. Results are most informative when compared with other peanut markers and overall IgA/IgG patterns on the Food Zoomer.

What does it mean if my Ara h 13 levels are high?

Higher Ara h 13 antibody levels show measurable immune recognition of that peanut protein. Elevated IgA may point toward mucosal gut-related antibody activity, while elevated IgG suggests broader systemic antibody response. These findings are signals to examine the full Food Zoomer pattern and clinical context rather than standalone conclusions.

Why is Ara h 13 included in the Food Zoomer?

Including Ara h 13 increases peptide-level resolution within the peanut domain, improving the panel’s ability to detect which peanut proteins drive immune activity. That added specificity helps providers identify clustered patterns across peanut peptides and combine this information with IgA/IgG trends to guide personalized nutrition planning.

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