What is Gly m 6 and Why Does the Food Zoomer Test for It?

Soy glycinin storage protein

Gly m 6 is a major soybean seed storage protein (part of the glycinin 11S globulin family) that can act as an immune target when soy is consumed. Measuring antibody responses to Gly m 6 helps reveal whether the immune system recognizes this specific soy protein, offering insight into food-related immune activity in the gut and systemically.

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Gly m 6

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About Gly m 6

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About Gly m 6

Overview and History

Gly m 6 is a protein naturally found in soybean seeds (Glycine max) and belongs to the glycinin family, an 11S globulin class of seed storage proteins. In plant biology it stores amino acids for seed germination; in clinical and allergy research Gly m 6 has been identified as one of the prominent soy protein components that can elicit immune recognition. Research into food proteins like Gly m 6 began with protein fractionation and immunoassays that mapped specific antibody responses to seed storage proteins. Its clinical relevance comes from repeated findings that antibodies can target glycinin subunits, so measuring responses to Gly m 6 provides a precise, protein-level view of how the immune system engages with soy components.

Interpreting Highs and Lows

Elevated antibody levels to Gly m 6 (IgA or IgG) suggest the immune system has recognized this soy storage protein and is producing a measurable response; IgA elevations are more suggestive of mucosal or gut-associated activity, while IgG elevations reflect systemic immune exposure. Low or undetectable levels suggest no measurable antibody response to this specific protein at the time of testing. Interpretation depends on the broader Food Zoomer profile: patterns across other soy antigens, IgA vs IgG balance, and responses to related food groups and peptides all inform whether isolated Gly m 6 reactivity is meaningful for an individual's dietary planning.

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Gly m 6 is included in Food Zoomer to provide protein-level precision for soy reactivity: it evaluates immune recognition of a major soy storage protein and helps place soy responses into the test's broader pattern analysis. That specificity supports more nuanced interpretation and targeted dietary planning within a comprehensive immune profile.

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Gly m 6 FAQs

What is Gly m 6 and why is it important?

Gly m 6 is a soybean seed storage protein commonly called glycinin. It’s important because the immune system can form antibodies that specifically recognize this protein, so measuring responses to Gly m 6 can clarify whether soy proteins are part of a person's immune pattern to foods.

What does it mean if my Gly m 6 levels are low?

Low or undetectable Gly m 6 antibody levels mean there’s no measurable immune recognition of this specific soy protein on the test. That does not rule out all soy-related responses—other soy proteins or broader food patterns on the Food Zoomer may still show activity—so results are interpreted in the context of the full panel.

What does it mean if my Gly m 6 levels are high?

High antibody levels to Gly m 6 indicate that the immune system has recognized this soy storage protein and produced measurable IgA and/or IgG responses. Elevated results suggest sensitization or immune engagement with this protein, but clinical significance requires review alongside other panel markers, symptom history, and provider interpretation.

Why is Gly m 6 measured on the Food Zoomer?

Including Gly m 6 gives protein-level detail for soy reactivity, helping providers distinguish which specific soy components trigger immune responses. That precision improves pattern detection across IgA and IgG, supports targeted dietary decision-making, and refines personalized nutrition planning.

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