What is Anti-Tubulin and Why Does the Neural Zoomer Test for It?

Neuronal cytoskeleton autoantibody

Anti-Tubulin antibodies target tubulin proteins that form neuronal microtubules. Because microtubules support neuron shape and intracellular transport, detecting these antibodies can indicate immune activity against structural neural components and help map neuroimmune patterns.

View Neural Zoomer

Anti-Tubulin

Quality and Security

High-quality testing run in a CLIA-certified and CAP-accredited lab in Santa Clara, California.

fortified-health-HIPAA-compliance-pqgjtx4popoe2n0arp68hrz8h2as5rlhgng5b2srk8 1

About Anti-Tubulin

${ activeTab.tab_content.text }

View ${ activeTab.tab_content.btn_label }

About Anti-Tubulin

Overview and History

Anti-Tubulin refers to autoantibodies that bind tubulin, the alpha/beta protein subunits that polymerize into microtubules. Tubulin is a core cytoskeletal protein present in all cells but is especially critical in neurons for maintaining shape, polarity, and long-distance transport along axons. Autoantibodies to cytoskeletal proteins have been described in clinical and research settings as part of broader neuroimmune investigations. Studying Anti-Tubulin offers a window into immune interactions with neuronal architecture and complements markers that assess inflammation, myelin-associated proteins, and synaptic receptors.

Interpreting Highs and Lows

Elevated Anti-Tubulin levels may reflect measurable immune activity directed at neuronal structural proteins. In clinical practice, such elevations are considered alongside symptoms and other panel markers because they can occur as part of broader neuroimmune patterns linked to changes in sensation, coordination, or nerve signaling. Low or undetectable Anti-Tubulin levels suggest little to no measurable antibody activity against tubulin at the time of testing. A low result does not rule out other immune processes, prior immune events, or non-immune causes for symptoms; interpretation requires correlation with the full Neural Zoomer panel and the clinical picture.

Featured Test

Anti-Tubulin is included in the Neural Zoomer to evaluate immune interactions with the neuronal cytoskeleton within the demyelination and structural integrity domain. It adds information about possible immune targeting of microtubule components, helping clinicians integrate structural-target data into a broader neuroimmune profile for more personalized follow-up and testing.

View Neural Zoomer

Anti-Tubulin FAQs

What is Anti-Tubulin and why is it important?

Anti-Tubulin are antibodies that bind the tubulin proteins making up neuronal microtubules. Microtubules keep neurons shaped and move materials along axons and dendrites. Finding these antibodies can signal that the immune system is interacting with neuronal structure, which may help explain certain nerve-related symptoms when viewed with other test results.

What does it mean if my Anti-Tubulin levels are low?

Low or undetectable Anti-Tubulin levels generally mean there is little measurable immune activity against tubulin at the time of testing. This does not rule out other immune markers or non-immune causes of symptoms. Clinicians interpret a low result together with the rest of the Neural Zoomer panel and the clinical history.

What does it mean if my Anti-Tubulin levels are high?

Higher Anti-Tubulin levels may indicate an immune response directed at neuronal structural proteins. Such elevations are an association rather than a standalone diagnosis and are interpreted in context with symptoms, other antibody results, imaging, and clinical exam to understand their potential significance.

Why is this biomarker included in the Neural Zoomer?

Measuring Anti-Tubulin helps reveal whether immune activity is targeting neuronal structural components, adding a structural dimension to the panel’s assessment. Combined with markers of myelin, synapses, and barrier integrity, it supports pattern recognition that can guide focused clinical evaluation and personalized testing strategies.

Browse Articles

Introducing the Gut-Brain Axis Featured Image

The Gut–Brain Axis: How Microbes Influence Mood and Mental Well-Being

The gut and brain are in constant communication, a bidirectional network that influences not only digestion and immunity, but also mood, focus, and be...

Christopher McLaughlin

Oct 31, 2025

Gut Health Neural Health Research & Innovation

How Histamine Affects Mental Health and Cognitive Function

When most people think of histamine, they picture allergy symptoms, sneezing, hives, and congestion. But histamine is far more than an allergy molecul...

Brendan Vermeire

Sep 9, 2025

Neural Health Longevity

How Mast Cells Contribute to Autoimmune Brain Disorders

Autoimmune brain disorders represent one of the most complex and misunderstood intersections of neurology and immunology. Conditions such as multiple ...

Brendan Vermeire

Sep 3, 2025

Neural Health Research & Innovation

How Mycotoxins Trigger Mast Cell Activation and Brain Inflammation

Many patients with chronic, unexplained symptoms have a history of mold exposure that’s never been fully explored. What begins as vague fatigue or hea...

Brendan Vermeire

Aug 13, 2025

Neural Health Toxins

About Vibrant:

The Experts Behind  Every Test

Our team is built on collaboration across disciplines to advance the science of wellness and longevity. At Vibrant Wellness, lab scientists, technologists, clinical researchers, doctors, practitioners, longevity advisors, engineers, and regulatory experts work side by side to transform diagnostics.

By uniting diverse expertise under one mission, we pioneer precision testing that empowers providers to uncover root causes, personalize care plans, and optimize patient health outcomes. Every test we develop reflects this commitment—to push boundaries in functional medicine, deliver clear, actionable insights, and support clinicians in helping patients live healthier, longer lives.

View All Tests

Results trusted by over 18,000 functional wellness professionals

We’re the leading provider of specialty wellness lab testing because we develop our testing with rigorous, ongoing research by top clinical experts, doctors, and scientists.

The gold standard of accuracy in  the lab industry

Our tests run on a proprietary 3Dense microchip technology platform that boasts unrivaled specificity and sensitivity. While most other labs carry only CLIA certification, we're CAP-accredited by the College of American Pathologists.

Our Clinical Support Team

We understand that patient care doesn't end with diagnosis. To achieve Vibrant health, patients need clinical support and
obtainable lifestyle changes. Our clinical support team helps providers make informed treatment recommendations, resulting in  better patient outcomes.

Mary Beth Augustine

DCN, RDN, FAND- Lead Clinical Educator

Suzanne Barker

MS, RDN, LD, CTTS, CGP- Clinical Educator

Suzette Garcia

MSc- MHNE- Clinical Educator

Brooke Mader Ganev

MS, CNS, LDN, FDN- Clinical Educator

Adair Anderson

MS, RDN, LDN- Clinical Educator

Lillie Luu Nguyen

DCN, CNS, LDN- Clinical Educator

Jason Barker

ND- Clinical Educator

Emaline Brown

ND- Clinical Educator

Dana Filatova

DCN, CNS, LDN- Clinical Educator

Jessy Dhanjal

ND- Clinical Educator

Nour Amri

MS, LDN, CNS, CKNS- Clinical Educator

Ready to Elevate Your Approach to Precision Wellness?

At Vibrant Wellness, we’re redefining the future of diagnostics—making complex science clear, accessible, and actionable. Whether you're a provider advancing personalized care or a patient seeking data-driven answers, our precision testing gives you the clarity to make informed decisions. Experience the next generation of functional medicine through clinically validated insights and seamless testing solutions.

Become a Provider

Become a Patient