Oxidatively modified LDL marker
Quality and Security
High-quality testing run in a CLIA-certified and CAP-accredited lab in Santa Clara, California.
About Oxidized LDL (ox-LDL)
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About Oxidized LDL (ox-LDL)
Overview and History
Oxidized LDL is not a separate lipoprotein class but LDL particles altered by oxidative chemical changes to their lipids and apolipoproteins. These modifications produce oxidized phospholipids and protein adducts that change how the particle interacts with cells and immune receptors.
Research into oxidized lipids began in the late 20th century as investigators explored how modified lipoproteins behave differently from native LDL. Biochemically, ox-LDL is detected by assays targeting oxidized epitopes or specific oxidation products; its presence signals altered redox balance and lipid handling rather than serving as a standalone organ or cell type.
Interpreting Highs and Lows
Higher ox-LDL levels often indicate increased lipid oxidation and greater oxidative or inflammatory activity in the vascular environment. In the context of other markers, elevated ox-LDL can highlight patterns of lipid dysfunction, oxidative stress, or immune activation.
Lower ox-LDL levels generally suggest less ongoing lipid oxidation, but interpretation depends on the whole panel. Low values should be considered alongside traditional lipids, inflammatory markers, antioxidant status, and clinical context to assess overall metabolic and vascular patterns.
Featured Test
Ox-LDL is included in the Foundation Zoomer because it evaluates lipid quality and oxidative burden as part of the Metabolic Cardiovascular domain. It helps providers detect patterns of lipid oxidation and vascular inflammation that standard lipid panels may miss, informing a systems-based view used for personalized care planning.
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We’re the leading provider of specialty wellness lab testing because we develop our testing with rigorous, ongoing research by top clinical experts, doctors, and scientists.
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The gold standard of accuracy in the lab industry
Our tests run on a proprietary 3Dense microchip technology platform that boasts unrivaled specificity and sensitivity. While most other labs carry only CLIA certification, we're CAP-accredited by the College of American Pathologists.
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Mary Beth Augustine
DCN, RDN, FAND- Lead Clinical Educator
Suzanne Barker
MS, RDN, LD, CTTS, CGP- Clinical Educator
Suzette Garcia
MSc- MHNE- Clinical Educator
Brooke Mader Ganev
MS, CNS, LDN, FDN- Clinical Educator
Adair Anderson
MS, RDN, LDN- Clinical Educator
Lillie Luu Nguyen
DCN, CNS, LDN- Clinical Educator
Jason Barker
ND- Clinical Educator
Emaline Brown
ND- Clinical Educator
Dana Filatova
DCN, CNS, LDN- Clinical Educator
Jessy Dhanjal
ND- Clinical Educator
Nour Amri
MS, LDN, CNS, CKNS- Clinical Educator
