Mastering the Gut-Brain Axis in Functional Psychiatry with Dr. James Greenblatt, MD

In this episode of the Vibrant Wellness Podcast, Dr. Emmie Brown, ND and Melissa Gentile sit down with Dr. James Greenblatt, a leading expert in integrative psychiatry.

Dr. Greenblatt explores how genetic factors like MTHFR mutations can influence psychiatric conditions and shares practical insights on using targeted nutritional and metabolic interventions in mental health care.

He highlights the impact of supplements—such as magnesium, vitamin B3, and ashwagandha—on managing anxiety and ADHD. The conversation delves into the gut-brain connection, the role of diet and heavy metal exposure in mental health, and the effects of screen time on cognitive and emotional well-being. Dr. Greenblatt also emphasizes the importance of blending personalized medicine with cautious pharmaceutical use to achieve optimal outcomes.

Whether you’re interested in functional medicine testing, integrative strategies for mental health, or actionable tips for your practice, this episode offers valuable takeaways for any practitioner.

Don’t miss this insightful discussion on how to better support your patients’ mental health through innovative, root-cause approaches.

Key Points:

🎙️ Introduction to Dr. Greenblatt and his holistic approach to psychiatry
🌱 The gut-brain axis: its role in mental health
🔍 Magnesium, vitamin B3, and omega-3s in treating anxiety
📊 Functional medicine testing for ADHD, anxiety, and depression
🧬 The importance of genetic testing and MTHFR insights
🛠️ Practical strategies for integrating functional medicine into mental health practices

Timestamps:

• 0:01 – Welcome and introduction of Dr. James Greenblatt
• 3:12 – Dr. Greenblatt’s journey to integrative psychiatry
• 6:45 – Gut-brain axis and its influence on mental health
• 10:33 – Role of magnesium and vitamin B3 in anxiety
• 15:22 – ADHD testing and the plus-minus treatment model
• 25:18 – The significance of genetic testing (e.g., MTHFR) in psychiatry
• 40:07 – Detox strategies and prioritization in functional care
• 50:50 – Advice for practitioners new to functional psychiatry 

Resources Mentioned:

• Psychiatry Redefined – Dr. Greenblatt’s training and resources

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