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In this episode of the Vibrant Wellness Podcast, hosts Dr. Emmie Brown, ND, and Melissa Gentile, INHC, sit down with Dr. Eric Fete, founder of Prime X and a recognized leader in preventive, age management, and performance medicine. He shares his expertise on “muscle medicine,” a systems-based approach recognizing skeletal muscle as a key endocrine organ central to metabolic health and healthy aging.
Dr. Fete explores the latest in peptide therapy, hormone optimization, and the often-overlooked roles of mitochondrial and gut health. He provides nuanced insights on everything from exercise design and recovery to quantum biology, offering practical takeaways for clinicians who want to merge cutting-edge interventions with strong lifestyle foundations. His approach bridges the gap between advanced medical tools and nutrition, sleep, and movement fundamentals, showing how both are essential for optimal health outcomes.
In this conversation, he unpacks how muscle functions as a key endocrine organ, why recovery is as important as training, and how to layer detox, hormonal support, and peptide therapies strategically. From the cognitive benefits of resistance training to the circadian “agenda” that aligns light exposure, meal timing, and movement, Dr. Eric Fete shares actionable strategies for improving longevity, performance, and resilience. His blend of science-backed protocols and accessible daily practices makes this episode valuable for practitioners and health enthusiasts.
🎙 Key Topics Covered
💪 Muscle as a key endocrine organ for longevity and metabolism
🍳 Debunking protein and strength training myths for women
🧬 Hormones, mitochondria, and detox in muscle preservation
🧪 Phased detox: inflammation reduction before rebuilding
💉 HRT for longevity — timing, dosing, and optimization
🧷 Peptides as advanced tools after lifestyle foundations
🏋️ “Recover harder” approach to training and rest
🚶 NEAT and daily walking for metabolic health
🧠 Exercise-driven cognitive and neuroplasticity gains
🌞 Circadian syncing for hormones, sleep, and recovery
🔥 Recovery tools: red light, sauna, and cold plunge
💧 Quantum biology basics — light, water, and movement
⏱️ Timestamps
0:00 – Why recovery is just as important as training: overtraining, cortisol, and letting the body heal.
0:37 – Introduction of guest Dr. Eric Fete and his background in preventive health, age management, and performance.
1:11 – Muscle as an endocrine organ and its role in longevity.
2:31 – Dr. Eric Fete’s lifelong interest in fitness, nutrition, and the science of body composition.
4:11 – Lessons from the ER: lifestyle counseling and seeing preventable illness at younger ages.
6:09 – Overlooked factors in preserving muscle: hormonal health, mitochondrial function, and toxin removal.
9:03 – Detox strategies, reducing inflammation first, and using peptides to support recovery.
11:01 – “Normal” vs. optimal hormone levels — why lab ranges can be misleading.
13:27 – Starting HRT with longevity in mind and when to begin (or if it’s ever too late).
17:11 – Peptide therapy: foundations first, then targeted support for muscle growth and recovery.
22:01 – “Recover harder to train smarter” — the case for rest and strategic training.
24:06 – A basic exercise template: strength training, daily walking, and smart cardio.
27:29 – Flipping the script: using short cardio bursts before lifting to prime muscle growth.
30:00 – Cognitive benefits of exercise and how muscle health supports brain function.
33:36 – NEAT and “exercise snacks” to keep movement up throughout the day.
33:49 – Lab testing approach: hormones, inflammation markers, lipid particle size, and leptin resistance.
37:12 – Circadian “agenda” for optimal metabolism, hormones, and recovery.
40:18 – Dr. Fete's personal daily routine, from sunrise grounding to evening wind-down.
45:34 – Using sauna and red light for recovery and mitochondrial health.
45:39 – Introduction to quantum biology: syncing light, water, and movement with circadian rhythms.
50:14 – Resources and books for learning more about quantum biology.
51:03 – Where to connect with Dr. Eric Fete online.
🔗 Resources Mentioned
🌐 Dr. Eric Fete's Website: https://www.drericprimex.com/
📘 Follow Dr. Eric Fete on LinkedIn: https://www.linkedin.com/in/eric-fete-90030346/
📸 Follow Dr. Eric Fete on Instagram: https://www.instagram.com/drericfete/
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Limitations
Please note the information provided by Vibrant Wellness is intended solely for research and informational purposes to help inform lifestyle choices aimed at potential risk mitigation. The information is not intended to be used by the patient for any diagnostic purpose and is not a substitute for medical advice by a healthcare practitioner. Please consult a licensed healthcare practitioner for any questions regarding diagnosis, prevention, or treatment of any disease or health assessment
