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In this episode of the Vibrant Wellness Podcast, Dr. Emmie Brown and Melissa Gentile are joined by Dr. Nirusha Kumaran, a UK-based GP, lifestyle medicine physician, and functional medicine doctor. Dr. Nirusha shares her clinical perspective on personalized BHRT, navigating perimenopause, and the overlooked impacts of hormone imbalance on women’s long-term health.
From testing strategies to real-world case studies, this conversation offers a comprehensive look at the evolving science, clinical decision-making, and personalized applications of hormone replacement therapy (HRT) in women’s health. Dr. Nirusha breaks down how BHRT can be used not just for symptom relief but as a proactive tool for prevention and longevity. The discussion covers the nuances of hormone selection, delivery methods, timing, and patient monitoring—along with how advanced testing methods like hormone metabolite analysis, genomic testing, and toxin screening are shaping individualized protocols.
🎙 Key Topics Covered
🌡️ Symptoms of perimenopause and menopause often missed in conventional medicine🧬 The difference between synthetic, bioidentical, and "body identical" hormones
💊 Personalized BHRT for prevention and longevity
🧪 How Dr. Nushá uses testing (blood, urine metabolites, genomics) to tailor HRT
🧠 Case study: Resolution of chronic symptoms with testosterone and progesterone
🌱 Integrative tools: Adaptogenic herbs, detoxification support, and lifestyle
⏱️ Timestamps
0:00 – Intro and overview of symptoms prompting BHRT
1:00 – Meet Dr. Nirusha Kumaran
2:05 – Why hormonal health matters at every life stage
4:45 – Dr. Nirusha's personal health journey and discovery of root-cause care
8:20 – Understanding the difference: Synthetic vs. bioidentical vs. body identical HRT
16:00 – Personalized timelines and long-term monitoring on BHRT
22:00 – Oral vs. topical hormones: What to choose and why
24:00 – Side effects and patient tolerability considerations
25:20 – Testosterone and DHEA in female HRT protocols
28:00 – Herbal therapies and adaptogens for adrenal and hormonal support
30:00 – How cortisol and adrenal dysfunction impact hormonal balance
34:00 – Case study: Blocked tear ducts resolved with testosterone + progesterone
39:00 – Musculoskeletal symptoms of menopause and hormone support
41:00 – BHRT as a tool for prevention and longevity
43:00 – Foundational lifestyle pillars for hormone health
45:00 – Detoxification, toxin exposure, and testing for environmental estrogens
🔗 Resources Mentioned
🔗 Hormone Zoomer with toxin insights: https://vibrant-wellness.com/tests/hormones/hormone-zoomer📸 Follow Dr. Nirusha Kumaran on Instagram: https://www.instagram.com/dr_nirusha.kumaran/
🔗 Dr. Nirusha on LinkedIn: https://www.linkedin.com/in/dr-nirusha-kumaran/
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